| ABSTRACT:
Herpes simplex virus (HSV) is a relatively common virus that can infect humans. HSV infections are endemic worldwide, affecting nearly 75% of the general population at some time during the life span. (1) The herpes simplex virus can invade the body and infect the skin, mucous membranes, nervous system, and the eye. (The term "herpes" is derived from the Greek work meaning to creep, probably because of the way herpetic lesions progress along the surface of the body and the cornea of the eye.)
HSV is a double-stranded DNA virus (Fig. 1) that enters host cells and replicates in their nuclei (i.e., the virus uses the cell's metabolic machinery to produce more virus particles). This ultimately leads to cell death, which releases viral particles to invade surrounding cells. HSV replicates rapidly in many different cell types, but replication is especially rapid in stratified squamous epithelium (e.g., the cornea and skin). |
Author(s):
Weon Jun, OD, FAAO
Company: Pacific University
Expire Date:
CE Credits: 3
Price: $59.00
CE Format: Online text/photos
COPE ID: 14382-AS
|